For the second time in three years, the Champions League final will be very domestic affair, with Real Madrid taking on local rivals Atlético Madrid at the San Siro in Milan on Saturday.
Manchester United will go in search of their first FA Cup trophy since 2004 when they face Crystal Palace in the final at Wembley on Saturday.
Ajax Cape Town play host to Bidvest Wits in the final round of Premiership fixtures at Cape Town Stadium on Saturday afternoon with nothing but pride to play for.
Mamelodi Sundowns will lift the Premiership title following their clash against Platinum Stars at the Lucas Moripe Stadium on Saturday.
Mpumalanga Black Aces will close their season against Free State Stars with some ambivalence at the Mbombela Stadium on Saturday.
Barcelona and Sevilla are both looking for their second major trophy of the season when they meet in the Copa del Rey final at Estadio Vicente Calderón on Sunday.
Bayern Munich manager Pep Guardiola will be hoping to end his tenure in Germany on a winning note when his side takes on BGundesliga runners-up Borussia Dortmund in the DFB-Pokal final on Saturday evening.
Orlando Pirates and SuperSport United meet in a league encounter on Saturday in Soweto in the first of two crucial matches between the two sides.
Chippa United will be looking to add further shine to what has been an accomplished season when they take on Kaizer Chiefs at the FNB Stadium on Saturday.
Jomo Cosmos and Maritzburg United will be fighting for their place in the Premiership when they meet at Olen Park in Potchefstroom on Saturday.
University of Pretoria will head into their final match of the season against Golden Arrows at Tuks Stadium on Saturday knowing that nothing less than victory will suffice.
Bloemfontein Celtic and Polokwane City close the curtain on disappointing Premiership seasons when they face each other in the final match at the Dr Molemela Stadium on Saturday.
Liverpool are looking to dethrone Europa League specialists Sevilla when they meet in the final at St Jakob-Park in Basel, Switzerland on Wednesday.
Mamelodi Sundowns will be hoping to show the form that won them the Premiership title recently when they take on Medeama in a crucial CAF Confederation Cup play-off tie on Wednesday.
- West Brom v Liverpool
- Manchester United v Bournemouth
- Everton v Norwich City
- Watford v Sunderland
- Stoke City v West Ham
- Southampton v Crystal Palace
- Swansea City v Manchester City
- Bayern Munich v Hannover
- Newcastle v Tottenham
- Chelsea v Leicester City
- FS Stars v Orlando Pirates
- Arsenal v Aston Villa
- Bidvest Wits v Mamelodi Sundowns
- Platinum Stars v Bloemfontein Celtic
- Sunderland v Everton
- Chippa United v Orlando Pirates
- SuperSport v Black Aces
- Free State Stars v Kaizer Chiefs
- Polokwane v University of Pretoria
- Liverpool v Chelsea
- Norwich City v Watford
- Golden Arrows v Jomo Cosmos
- Maritzburg United v Ajax Cape Town
- West Ham v Manchester United
- Crystal Palace v Stoke City