Orlando Pirates will renew their rivalry with Bidvest Wits when they clash in a Premiership match at the Orlando Stadium on Saturday.
Manchester United welcome Queens Park Rangers to Old Trafford on Sunday still searching for their first win of the new Premier League season.
Stoke City will be targeting more of the same when they take on new boys Leicester City at the Britannia Stadium on Saturday afternoon.
Crystal Palace lock horns with fellow stragglers Burnley at Selhurst Park on Saturday as they look to lift themselves out of the relegation zone.
Bloemfontein Celtic and Mamelodi Sundowns return to Premiership action in a mid-table clash at the Free State Stadium on Sunday afternoon.
Sunderland welcome Tottenham to the Stadium of Light on Saturday as they look to record their first win of the new campaign.
Southampton will be targeting back-to-back victories for the first time this season when Newcastle visit St Mary's on Saturday.
Liverpool and Aston Villa have both enjoyed productive starts to the season, but that trend is likely to end for one of the clubs come Saturday.
Everton will be hoping to demonstrate some renewed defensive strength when they head to West Brom on Saturday.
Polokwane City will be without new coach Kosta Papic when they take on AmaZulu in their bottom-of-the-table Premiership clash on Saturday.
Chiefs will be looking to maintain their 100 percent start when they host the University of Pretoria at the FNB Stadium on Saturday.
Ajax Cape Town will be looking to continue their strong start to the season when they welcome Free State Stars to the Athlone Stadium on Saturday.
A packed Dobsonville Stadium is expected when Moroka Swallows welcome Chippa United for a Premiership encounter on Sunday.
Chelsea and Swansea City will lock horns in an unexpected top of the table clash in the Premier League on Saturday.
- Maritzburg Utd v Black Aces
- Arsenal v Manchester City
- South Africa v Nigeria
- Andorra v Wales
- Switzerland v England
- Hungary v Northern Ireland
- Georgia v Rep of Ireland
- Germany v Scotland
- Sudan v South Africa
- England v Norway
- Republic of Ireland v Oman
- Leicester v Arsenal
- Tottenham v Liverpool
- Swansea v West Brom
- QPR v Sunderland
- Aces v University of Pretoria
- Polokwane City v Pirates
- Newcastle v Crystal Palace
- Everton v Chelsea
- Free State Stars v Maritzburg
- Sundowns v AmaZulu
- West Ham v Southampton
- Chiefs v SuperSport United
- Manchester City v Stoke City
- Burnley v Manchester United