Southampton will make their historic return to European football on Thursday when they host Vitesse in Europa League qualifying action.
South Africa will be expected to take the next step towards the African Nations Championship finals when they face Mauritius in the second leg of their preliminary round clash on Sunday.
Orlando Pirates will be hoping to maintain their 100 per cent run in the CAF Confederations Cup when they host Zamalek on Saturday.
Orlando Pirates will be hoping to continue their fine continental form when they kick off the group stages of the CAF Confederations Cup, against AC Leopards, on Saturday.
Northern Ireland boss Michael O'Neill is downplaying the significance of their Euro 2016 qualifier against Romania at Windsor Park on Saturday.
Scotland face the Republic of Ireland at Aviva Stadium in Dublin on Saturday, when losing will mean falling off the pace in Euro 2016 qualifying Group D.
England will look to maintain their 100 per cent record in the Euro 2016 qualifiers when they travel to Stadion Stozice to face Slovenia on Sunday.
Bafana Bafana will be desperate to get back to winning ways when they welcome Gambia to the Moses Mabhida Stadium for their opening African Cup of Nations qualifier.
South Africa will be looking to end their goal drought when they face Angola in a friendly international at the Cape Town Stadium on Tuesday.
South Africa will begin their African Nations Championship campaign against Mauritius on Saturday, but do so without a host of first-choice players.
Wales welcome Belgium to the Millennium Stadium on Friday evening for their Euro 2016 qualifier knowing that a win will take them top of Group B.
This year's UEFA Champions League final in Berlin pits Juventus against Barcelona for the first time in the competition's illustrious history.
Orlando Pirates are favourites to reach the CAF Confederation Cup group stages when they host AS Kaloum at the Bidvest Stadium on Saturday.
The Republic of Ireland and England will lock horns in Dublin for the first time in 20 years for a friendly international on Sunday.
- Scotland v Qatar
- Moroka Swallows v Cosmos
- Arsenal v Aston Villa
- Leopards v Swallows
- Dnipro v Sevilla
- Jomo Cosmos v Leopards
- Aston Villa v Burnley
- Manchester City v Southampton
- Chelsea v Sunderland
- Jomo Cosmos v Swallows
- Leicester City v QPR
- Stoke v Liverpool
- Crystal Palace v Swansea
- Everton v Tottenham
- Hull City v Man United
- Newcastle v West Ham
- South Africa v Botswana
- Arsenal v Sunderland
- Swallows v Black Leopards
- West Brom v Chelsea
- Manchester United v Arsenal
- West Ham v Everton
- Swansea v Manchester City
- Sunderland v Leicester
- Liverpool v Crystal Palace