Northern Ireland boss Michael O'Neill is downplaying the significance of their Euro 2016 qualifier against Romania at Windsor Park on Saturday.
Scotland face the Republic of Ireland at Aviva Stadium in Dublin on Saturday, when losing will mean falling off the pace in Euro 2016 qualifying Group D.
England will look to maintain their 100 per cent record in the Euro 2016 qualifiers when they travel to Stadion Stozice to face Slovenia on Sunday.
Bafana Bafana will be desperate to get back to winning ways when they welcome Gambia to the Moses Mabhida Stadium for their opening African Cup of Nations qualifier.
South Africa will be looking to end their goal drought when they face Angola in a friendly international at the Cape Town Stadium on Tuesday.
South Africa will begin their African Nations Championship campaign against Mauritius on Saturday, but do so without a host of first-choice players.
Wales welcome Belgium to the Millennium Stadium on Friday evening for their Euro 2016 qualifier knowing that a win will take them top of Group B.
This year's UEFA Champions League final in Berlin pits Juventus against Barcelona for the first time in the competition's illustrious history.
Orlando Pirates are favourites to reach the CAF Confederation Cup group stages when they host AS Kaloum at the Bidvest Stadium on Saturday.
The Republic of Ireland and England will lock horns in Dublin for the first time in 20 years for a friendly international on Sunday.
Scotland will continue their preparations ahead of the upcoming Euro 2016 qualifiers with a friendly international against 2022 World Cup hosts Qatar on Friday.
Jomo Cosmos have their Premiership promotion fate in their own hands as they prepare to face a down and out Moroka Swallows in the final play-off fixture at the Dobsonville Stadium on Wednesday.
Arsenal will be without Danny Welbeck when they take on Aston Villa in the FA Cup final at Wembley on Saturday afternoon.
Moroka Swallows have a chance to retake the lead in the Premiership play-off standings, but need to rediscover their form against Black Leopards at Thohoyandou Stadium on Sunday.
- Dnipro v Sevilla
- Jomo Cosmos v Leopards
- Aston Villa v Burnley
- Manchester City v Southampton
- Chelsea v Sunderland
- Jomo Cosmos v Swallows
- Leicester City v QPR
- Stoke v Liverpool
- Crystal Palace v Swansea
- Everton v Tottenham
- Hull City v Man United
- Newcastle v West Ham
- South Africa v Botswana
- Arsenal v Sunderland
- Swallows v Black Leopards
- West Brom v Chelsea
- Manchester United v Arsenal
- West Ham v Everton
- Swansea v Manchester City
- Sunderland v Leicester
- Liverpool v Crystal Palace
- Burnley v Stoke
- Southampton v Aston Villa
- Tottenham v Hull
- QPR v Newcastle