Sir Alex Ferguson will look to sign off in style when Manchester United travel to West Brom on the final day of the Premier League season.
Swansea welcome Fulham to the Liberty Stadium on the final day of the season hoping to close out the campaign with a win.
Tottenham's Champions League hopes come down to the final day of the season at home to Sunderland on Sunday afternoon.
Arsenal travel to Newcastle on the final day of the season knowing a win will guarantee them UEFA Champions League football next season.
Ajax Cape Town will be hoping to prevent Chippa United from toppling them out of the safety zone when they host Golden Arrows on Saturday.
Chippa need to beat AmaZulu in their final PSL clash to avoid the prospect of relegation from South Africa's top-flight.
Rafa Benitez and David Moyes take charge of their final games at Chelsea and Everton respectively when they meet on Sunday.
Barcelona will have their eye on the La Liga points record, and will look to take the next step towards that against Real Valladolid.
Platinum Stars will be hoping to see off SuperSport United and end the Premier Soccer League season in second place.
Southampton entertain Stoke City at St Mary's on the final day of the season with both clubs relieved to have beaten the drop.
FA Cup winners Wigan take on Aston Villa at the DW Stadium on Sunday afternoon in what will be their final Premier League fixture.
Managerless Manchester City play their final game of the season at the Etihad Stadium against Norwich City on Sunday.
Free State Stars entertain basement outfit Black Leopards on Saturday with the visitors' top-flight status hanging by a thread.
Liverpool legend Jamie Carragher will play his last game as a professional as the Reds host Queens Park Rangers at Anfield on Sunday.
- Moroka Swallows v Celtic
- Sundowns v Bidvest Wits
- Pirates v Maritzburg United
- Pretoria University v Chiefs
- Real Madrid v Atletico Madrid
- Orlando Pirates v Leopards
- Kaizer Chiefs v SuperSport
- Benfica v Chelsea
- Arsenal v Wigan
- Reading v Manchester City
- Bidvest Wits 3-1 AmaZulu
- Atletico Madrid v Barcelona
- Everton v West Ham United