West Brom will attempt to do the season double over Tottenham when the two teams lock horns at the Hawthorns on Saturday.
Chelsea will have the chance to stretch further ahead at the Premier League summit when Manchester City visit Stamford Bridge on Saturday.
Ivory Coast will see Sunday's quarter-final against Algeria in Malabo as an opportunity to exact some revenge in what is the pick of this weekend's Africa Cup of Nations action.
Arsenal will be looking to climb into the top four of the Premier League when they host Aston Villa at the Emirates Stadium on Sunday.
Relegation-threatened sides Sunderland and Burnley go head to head in a Premier League encounter at the Stadium of Light on Saturday.
Crystal Palace are level on points with Everton as the sides prepare to meet in a Premier League fixture at Selhurst Park on Saturday.
Manchester United will be out for revenge when they welcome Leicester City to Old Trafford for their Premier League encounter on Saturday.
Liverpool welcome West Ham on Anfield on Saturday with just one place and one point separating the two teams in the Premier League standings.
Newcastle United caretaker manager John Carver is still searching for his first win, and will be hopeful of getting it against Hull City at the KC Stadium on Saturday.
Guinea will be hoping their good fortune at the 2015 Africa Cup of Nations continues when they meet Ghana in a quarter-final clash in Malabo on Sunday.
Guinea lock horns with Mali in a crunch clash at Estadio de Mongomo on Wednesday with qualification from Group D still very much up in the air.
Ivory Coast head into their final group D clash with Cameroon on Wednesday knowing that only a win will guarantee their progress to the knockout phase.
Liverpool will be looking to heap further woe on Chelsea when they meet the London club at Stamford Bridge in the second leg of the Capital One Cup semi-final.
Islam Slimani will not be available for selection when Algeria play against Senegal in the Africa Cup of Nations on Tuesday.
- South Africa v Ghana
- Rochdale v Stoke
- DR Congo v Tunisia
- Cape Verde v Zambia
- Aston Villa v Bournemouth
- Congo v Burkina Faso
- Gabon v Equatorial Guinea
- Chelsea v Bradford
- Southampton v Crystal Palace
- Cameroon v Guinea
- Tottenham v Leicester
- Birmingham v West Brom
- Bristol City v West Ham
- Blackburn v Swansea
- Brighton v Arsenal
- Sunderland v Fulham
- Man City v Middlesbrough
- Liverpool v Bolton
- Ivory Coast v Mali
- Cambridge Utd v Man Utd
- Ghana v Algeria
- South Africa v Senegal
- Cape Verde v DR Congo
- Zambia v Tunisia
- Eq Guinea v Burkina Faso