Stoke will look to strengthen their place in the top-10 when they welcome struggling Everton to the Britannia Stadium on Wednesday night.
Manchester United will attempt to cement their place in the top-four when they take on Newcastle at St James' Park on Wednesday night.
Kaizer Chiefs will be targeting a return to winning ways in the Premiership when Ajax Cape Town make the trip to the FNB Stadium on Wednesday night.
Chippa United are hoping to climb the Premiership table when they welcome Polokwane City to the Nelson Mandela Bay Stadium on Wednesday.
Tottenham will be desperate to get a result against Swansea when the teams meet at White Hart Lane in the Premier League on Wednesday.
Arsenal travel to Lofuts Road to take on Queens Park Rangers looking to make it four league wins in a row following Saturday's 2-0 win over Everton.
League leaders Chelsea will look to extend their five point advantage when they travel across London to face West Ham at Upton Park on Wednesday.
Liverpool will be looking to extend their unbeaten run to 12 games when they host Burnley at Anfield on Wednesday evening.
Free State Stars will be looking to take advantage of Orlando Pirates' defensive weaknesses when they welcome the Bucs to Free State Stadium on Wednesday.
Manchester City will look to get back to winning ways when they host Leicester City at the Etihad on Wednesday evening.
Aston Villa will be desperate for points when West Brom make the short trip to Villa Park on Tuesday, before meeting again in the FA Cup quarter-final four days later.
Just a single point separates Hull City from relegation-threatened Sunderland prior to their meeting at the KC Stadium on Tuesday.
Sundowns and Wits will both have the chance to put the pressure firmly on Premiership leaders Chiefs when they lock horns at the Bidvest Stadium on Tuesday.
Platinum Stars will be looking to haul themselves out of the relegation zone when they head to the Free State Stadium on Sunday to face Bloemfontein Celtic.
- Stoke City v Hull City
- West Ham v Crystal Palace
- Man Utd v Sunderland
- Chelsea v Tottenham
- Township Rollers v Kaizer Chiefs
- Arsenal v Everton
- Maritzburg v Free State Stars
- Liverpool v Manchester City
- Burnley v Swansea City
- Pretoria Uni v MP Black Aces
- Orlando Pirates v Polokwane
- Costa shoots for glory
- No goal glut at Emirates
- Flag day at Anfield
- Sakho to hammer Palace
- SuperSport United v AmaZulu
- Chelsea make supporter plea
- Ajax CT v Chippa United
- Pretoria University v Swallows
- SuperSport v Polokwane City
- Parker: We'll be ready for Rollers
- Everton v BSC Young Boys
- Besiktas v Liverpool
- Fiorentina v Tottenham
- Wenger wary of Monaco defence